Dr. Sanjay Gupta: Pandemic Proofing Your Life Is Not What You Think

Dr. Sanjay Gupta: Pandemic Proofing Your Life Is Not What You Think

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(CNN)I have bad news for you: We’re stuck with this novel coronavirus in our environment perhaps indefinitely. And there might be another, more deadly and contagious pathogen right behind it that’s poised to dart around the world and stir yet another pandemic. But here’s the good news: Pandemic proofing your life is easier than you think, and it’s not about building a bunker or megadosing on supplements and waiting white-knuckled for the next booster shot. A remarkable suit of armor is already within you.

In the midst of a global pandemic, we’ve all changed. I joke that you’ve either become a chunk, monk, hunk or drunk. But seriously, what surprised me in my research into how we can prevent serious illness and death — and prepare for the next globetrotting scourge — is the key role diets play in our immune system and response to any infection, not just Covid.

As we all know, Covid has shined a big light on the difference between people who contract the virus with underlying conditions already and those who are otherwise healthy. But the conversation often unfairly revolves around obesity, which has the unfortunate result of objectifying and stigmatizing people. The recent uproar over comments made by the CEO of the salad chain Sweetgreen is a testament to how divisive this conversation can become. More importantly, it does a disservice to it because the connection between obesity and Covid mortality is complicated.

To be clear, suggesting that stamping out obesity will somehow be easier than mass vaccination, which the Sweetgreen CEO seemed to do, is patently false. But a deeper dive into nearly two years’ worth of data tells an important story that does not need to focus on weight or body size; and this one that doesn’t get enough attention.

More than a third of Americans have what’s called metabolic syndrome, and that number increases to nearly half of those age 60 and over. That’s a lot of vulnerable hosts for a stealthy pathogen. You don’t even have to be a single pound overweight to have metabolic syndrome, which refers to a cluster of common conditions that increase the risk of heart disease, stroke, diabetes, sleep apnea, liver and kidney disease, cancer, Alzheimer’s, and dying from an infection. In addition to excess body mass, these conditions include high blood pressure, abnormal cholesterol levels, and high blood sugar — the invisible signs of an unhealthy body. And if you can check these three boxes regardless of weight, you qualify as having the syndrome, which is easily stoked and perpetuated by diet. Many medical experts say that metabolic syndrome may be the most common and serious condition you’ve never heard of, and yet it’s playing mightily into people’s outcomes from Covid.

So, how does your diet adversely affect immune function? Some of it is direct. Food can spark or, conversely, subdue levels of inflammation. Our daily sustenance also constantly serves and regulates your intestinal microbiome — the gut’s internal “friendly” germ factory that plays mightily into immunity.

Studies in the past year alone have highlighted the significance of the microbiome in people’s prognosis with Covid. Associations found between gut microbiota composition (that is, strains and volume of species) and levels of inflammatory markers in patients with Covid suggest that the gut microbiome is involved in determining the magnitude of the infection. In other words, a significant predictor of just how ill you are likely to become is the status of your gut microbiome at the time you are infected. And, there is little question that metabolic dysfunction is associated with an imbalanced gut flora.

That also seems to be true for what happens to people after Covid-19 has cleared the body.

The health of the gut’s biome could be a major cause of long-hauler or post-Covid symptoms — brain fog, fatigue, and other persistent symptoms that remain after the initial infection runs its course. All of this means one of the easiest, most effective hacks to boost your immunity and protect yourself against disease in general is to eat healthier to keep weight in check, nurture your microbiome, and support a humming metabolism.

No, salads won’t replace vaccines or masks, but they are a terrific complement to all the other preventive measures we can take to stay out of harm’s way.

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Dr. Sanjay Gupta: Pandemic proofing your life is not what you think

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